High Blood Pressure

MAC Clinical Research is currently conducting a clinical trial to evaluate an investigational drug for hypertension (high blood pressure). Untreated hypertension can increase the risk of several other health problems, including heart attack, so it is important to treat high blood pressure. While several treatments already exist, many patients are not adequately controlled on these medications and research to discover better treatments is needed.

This trial will test the safety and efficacy of the investigational study drug compared to placebo (inactive pill) on patients with high blood pressure. The study medication or placebo will be given to you once and will be given as 1 injection with a thin needle under the skin of either your abdomen, upper arm or thigh.

There will be 12 visits to the clinic and 2 overnight stays over a period of up to 52 weeks. There is no certainty that you will receive any medical benefit from taking part in this study.

Criteria:

Key Inclusion Criteria:

• Male or female aged 18 to 65
• Diagnosis of hypertension
• BMI between 18 and 35 kg/m2, inclusive

Key Exclusion Criteria:

• Diagnosis or early onset diabetes
• Other unstable health condition
• Current smoker

Other eligibility criteria will apply. Please contact MAC for more information.

Any other information

Eligible patients will receive a comprehensive health screen and study participation will be in collaboration with the patient’s treating physician.