Sickle Cell Disease/Anaemia
Clinical Trial Enrolling Now

Clinics: Greater Manchester EPU

Therapy Area: Haematology

Gender and Age: Males & Females aged 18 – 60

Reimbursement: Up to £940 plus travel expenses

About The Research...

Sickle cell disease (SCD) or Sickle cell anaemia (SCA) is a genetic blood disorder that occurs when someone has abnormal haemoglobin on their red blood cell called Haemoglobin S (normal haemoglobin type is A). Sickle cell disease changes the shape of a person’s red blood cells. They are normally round and concave but SCD changes them to become long and stiff, forming the shape of a sickle. These sickle-shaped blood cells don’t flow through veins and arteries easily which leads to them clumping up and clogging the blood vessels. In turn, blood and oxygen can’t get through, and parts of the body (like the heart, lungs, and kidneys) can’t work the way they should. The blockage also causes pain or crises.

The purpose of this study is to learn more about how a potential new drug for treating SCD symptoms affects the body and how the body processes it.

This trial will run at our Greater Manchester EPU clinic and will last approximately 54 days in total with 7 outpatient visits and 1 x 2-night residential stay.

Criteria:

Key Inclusion Criteria

  • Age of between 18 and 60 years old
  • Diagnosis of sickle cell disease
  • No SCD crises in past 30 days before administration of the study drug.

Key Exclusion Criteria

  • History of stroke
  • Weighing over 110kg or less than 50 kg

Other eligibility criteria will apply. Please contact 0800 633 5507 for more information.​

Any other information

Eligible patients will receive a comprehensive health screen and study participation will be in collaboration with the patient’s treating physician.

Key Inclusion Criteria

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Key Exclusion Criteria

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MAC Clinical Research is conducting a trial to evaluate a potential new treatment for sickle cell disease.

If you would like more information, please fill in the form below and we will be in touch…

Alternatively, please call our recruitment team on freephone 0800 633 5507.

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