Healthy Volunteers

Clinics: Merseyside

Therapy Area: Healthy Volunteers

Gender and Age: Males & Females aged 18 – 55

Reimbursement: Between £1000 and £1710 plus reasonable travel expenses

Healthy Volunteers Research

About The Research...

Clinical research projects are performed as a way of bringing about progress in medicine and research. Clinical research projects make it possible to scientifically assess the properties of a drug, to demonstrate the effectiveness and safety of a treatment or a medical device, or to learn more about a disease and methods to diagnose and monitor it.

The purpose of this trial is to test the study drug COMP360 which is being developed for the treatment of depression.

There is an unmet need for new and improved treatments to help those suffering from low mood and depression. Many people do not respond appropriately or suffer side-effects from current approved medications, which can result in patients not taking them.

The study medication COMP360 is a man-made form of the psychedelic drug psilocybin. Psilocybin is a controlled drug and a chemical compound found in some species of mushrooms. Recent studies have suggested that psilocybin may help in treating depression due to its action on the serotonin system in the brain which is linked to the regulation of mood.

Following a successful medical screen and upon review of your medical history you will be required to attend one of the following 2 options (PK or FE Study): 

PK Study

1 x Pre-screen Chat, 1 x 1-night residential stay, 2 x outpatient visits and 1 x phone call over a period of approximately 7 weeks.

FE Study

1 x Pre-screen Chat, 2 x 1-night residential stays, 3 x outpatient visits and 1 x phone call over a period of approximately 9 weeks.

A full description of the study will be given before you decide to take part, both over the phone and during an appointment at a MAC clinic. This will include you receiving the full patient information sheet (PIS). Your GP will also be notified of your participation.

By participating in this clinical trial, you may be helping to contribute to the development of a new treatment option for people suffering from low mood and depression.

Reimbursement: Between £1000 and £1710 plus reasonable travel expenses


Key Inclusion Criteria:

  • Male or Female aged 18 to 55.
  • BMI 18.5 to 30 kg/m2.
  • Must be in good health as determined by medical and psychiatric history, medical examination, ECG and blood tests.


Key Exclusion Criteria:

  • Concerns about having blood taken.
  • Currently using any prescription or non-prescription medications (OTC). Occasional use of paracetamol is permitted.
  • Smoked (including e-cigarettes) within the last year.


Other eligibility criteria will apply. Please contact MAC for more information.

Any other information

If you are eligible you will receive a comprehensive health screen. Your GP will be fully informed of your participation and provided with any information relevant to your healthcare.

Key Inclusion Criteria


Key Exclusion Criteria


MAC Clinical Research is currently conducting a new clinical research study for Male and Female Healthy Volunteers.

If you would like more information, please fill in the form below and we will be in touch…

Alternatively, please call our recruitment team on freephone 0800 633 5507.

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