About This clinical research study
We are currently working to develop treatments which could be used to treat several nervous system conditions. However, we need healthy male volunteers to make this happen.
45 healthy male participants will take part in this study at our Greater Manchester clinic.
Participants will be required to attend 13 visits over approx. 10 months and the trial will assess and compare the safety and tolerability of three study medications (all marketed products): Dysport, Botulinum Toxin or Xeomin.
The results of the study may help provide treatment options for people living with nervous system conditions e.g., involuntary spasms, cramps and tremors and aesthetic or beauty treatments e.g., reducing the appearance of facial lines.
£2320 plus reasonable travel expenses
Clinics
Greater Manchester Early Phase Unit
Therapy Area
Healthy Volunteers
Gender and Age
Males aged between 18 - 65
A full description of the study will be given before you decide to take part, both over the phone and during an appointment at a MAC clinic. This will include you receiving the full patient information sheet (PIS). Your GP will also be notified of your participation.
If you contact us, it does not mean you have to decide at that point whether to participate.
If you do decide to participate you are free to withdraw at any time.
Interested volunteers will be required to undergo a full medical screening and those who are eligible will receive one single injection of either Dysport, Botulinum Toxin or Xeomin into the muscle on the outer side of the foot to induce a temporary weakness. Any weakness in this muscle caused by the study drugs will have no impact on walking.
It is only upon review of your screening results and medical history that will we know if you are suitable to take part in the study.
Reimbursement: £2320 plus reasonable travel expenses
Key Inclusion Criteria
- Males aged 18 – 65
- BMI 18 to 30 kg/m2
- Must be in good health as determined by medical and psychiatric history, medical examination, ECG and blood tests
Key Exclusion Criteria
- Concerns about having blood taken
- Currently using any prescription or over the counter (OTC) medications
- Received Botulinum Toxin treatments in the last 6 months
- Pending foot surgery
- Diagnosis of any nerve related conditions e.g., diabetic foot pain or any neuromuscular conditions e.g., myasthenia gravis
Other eligibility criteria will apply. Please contact MAC for more information.
If you are eligible, you will receive a comprehensive health screen. Your GP will be fully informed of your participation and provided with any information relevant to your healthcare.
ABOUT CLINICAL RESEARCH STUDIES
Clinical research studies are performed as a way of bringing about progress in medicine and research. Clinical research studies make it possible to scientifically assess the properties of a drug, to demonstrate the effectiveness and safety of a treatment or a medical device, or to learn more about a disease and methods to diagnose and monitor it.
If the study is successful, it may be an important step towards developing a promising new treatment.
MAC Clinical Research is currently conducting a new clinical research study for Male Healthy Volunteers.
If you would like more information, please fill in the form below and we will be in touch…
Alternatively, please call our recruitment team on freephone 0800 633 5507.
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