Dementia with Lewy bodies

Clinics: Greater Manchester, Lancashire and South Yorkshire

Therapy Area: Dementia with Lewy bodies

Gender and Age: Males & Females aged 50 – 80

Reimbursement: £680 plus travel expenses are reimbursed, or travel in a taxi is provided.

About The Research...

We are currently conducting a study to test a medication for people with Dementia with Lewy bodies (DLB, sometimes called Lewy Body Dementia (LBD)).  

What are Lewy bodies? These are small clumps of protein which form inside brain cells and damage areas of the brain, causing a decline in cognition, for example with attention, remembering, thinking and problem-solving.

The research team at MAC Clinical Research are conducting the trial into an existing medicine to see if the medication may help with cognition, in the hope that it may be repurposed as a potential new treatment for DLB.

People living with dementia with the presence of Lewy bodies often experience changes in concentration, attention, alertness, and wakefulness from day to day and sometimes throughout the day. His or her flow of ideas may be disorganized, unclear, or illogical at times. The person may seem better one day, then worse the next day. Researchers are investigating this treatment for Dementia with Lewy bodies, in the hope that it may help with some of these symptoms.

Developing a brand-new medicine takes an enormous amount of time, money and effort. Getting a promising new treatment into an approved medication can take around 14 years. It is crucial to advance strategies to reduce this time frame and improve success rates and drug repurposing is one such strategy.

Medications approved for other conditions have already been tested in people, so detailed information is available on their safety. Because repurposing builds upon previous research and development efforts, new therapies could be ready for large clinical trials quickly, speeding up their integration into health care.

All eligible participants will receive the study medication at some point during the trial.

A full description of the study would be given to you before you decide to take part, both over the phone and during an appointment at the MAC clinic. This will include you receiving the full patient information sheet (PIS). Your GP will also be notified of your participation.

Reimbursement: £680 plus travel expenses are reimbursed, or travel in a taxi is provided.

Criteria

Key Inclusion Criteria:

  • Age 50 – 80
  • Diagnosis of Dementia with Lewy bodies
  • The participant must have a study partner. This is someone who routinely accompanies and/or stays with the subject 12 hours or more a week and is able to accompany the subject to clinic visits.

 

Key Exclusion Criteria:

  • Unable to attend study visits or comply with study restrictions

 

Other eligibility criteria will apply. Please contact MAC for more information.

Any other information

Eligible patients will receive a comprehensive health screen and study participation will be in collaboration with the patient’s treating physician.

Key Inclusion Criteria

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Key Exclusion Criteria

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If you would like more information, please fill in the form below and we will be in touch…

Alternatively, please call our recruitment team on freephone 0800 633 5507.

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