Crohn's Disease / Ulcerative Colitis
Clinical Trials

Researching potential new treatments for Crohn’s Disease (CD) and Ulcerative Colitis (UC).

Improving quality of life

Key Information


You may be compensated for your time or reasonable travel expenses will be reimbursed or transport provided

Gender and Age

Males and Females aged 18 - 75


Greater Manchester, Lancashire, Merseyside, South Staffordshire, South Yorkshire and West Yorkshire

Not all trials are available at all clinics.

Health Check

Receive a free comprehensive health check

Register Your Interest

Data Privacy Statement
“At MAC we are researching into investigational medications and potential new treatments for crohn's and colitis. Autoimmune and inflammatory diseases such as UC and CD can happen when a person’s immune system becomes unbalanced, and it is estimated that around 1 in 400 people in the UK have some form of Inflammatory Bowel Disease. We want to help find ways to help reduce flare-ups and improve the quality of life for people living with these conditions, but we can only do that with the help of clinical trial volunteers.”
Dr Aliya Asher
Principal Investigator

What Happens Next?

What happens next?

1. Sign Up

Register your interest on our website or over the phone

2. We'll Call You

Our study specialists will call you to discuss your health and check if the trial is suitable for you

3. Eligible?

If eligible, you will be booked in for a 'CHAT' where you'll receive a Patient Information Sheet (PIS)

4. Medical History

If you decide to take part, our medical team will obtain a copy of your medical history from your GP

5. Health Check

You will attend a free comprehensive health check with a MAC doctor and your eligibility will be confirmed

6. Enrollment

You will be enrolled onto the clinical trial and attend scheduled visits (Travel expenses or transport to clinic provided)

About our Ulcerative Colitis & Crohn's Disease Clinical Trials

Clinical trials are research projects, performed as a way of bringing about progress in medicine and research. If you have Crohn’s or colitis, you may be eligible to participate in one of our clinical trials. We are currently recruiting volunteers to take part in a Crohn’s Disease (moderate to severe) clinical trial and Ulcerative Colitis (mild/moderate to severe) clinical trials.

Frequently Asked Questions

Ulcerative colitis and Crohn’s disease are the most common forms of Inflammatory bowel disease (IBD), an umbrella term for a group of intestinal disorders causing inflammation of the digestive tract. Both are long-term conditions, often developing in teenagers or young adults and symptoms can be similar including, but not limited to, diarrhoea, rectal bleeding, stomach cramps and fatigue. Some of the key differences between these conditions are: ulcerative colitis is limited to the large intestine (colon), but Crohn’s can occur anywhere in the digestive tract between the mouth and anus, also Crohn’s can leave healthy parts of the intestine between inflamed areas, whereas ulcerative colitis leaves a continuous line of inflammation in the colon.

All clinical trials must be reviewed and authorised by various governing bodies and committees before they can go ahead to minimise any risks. The Medicines and Healthcare products Regulatory Agency (MHRA) ensures that medicines meet applicable standards of safety, quality and efficacy, meaning a trial must be thought to be safe before it is approved. The Health Research Authority (HRA) is responsible for research ethics committees across the UK. Independent research ethics committees work to protect the interests and rights of volunteers who take part in the trial, adding another layer of protection to the process.

Clinical trials go through a series of phases to test new investigational medicines and assess whether they are safe and effective. These investigational medicines are tested against another treatment, called a control, which is either a placebo (a dummy treatment with no active ingredients) or a standard treatment already in use. Volunteers are randomly assigned to receive either the investigational medicine or the control treatment, these groups are often referred to as cohorts. Researchers monitor the effects of the investigational and control treatments within participants to assess the safety and efficacy of the treatments administered.

Clinical drug trials help doctors to discover new ways to treat a particular illness and are a crucial step in advancing medicine. Volunteers who take part in clinical trials can help to advance medical treatments for a condition, which could benefit themselves as well as other people in the future, however, there is no guarantee that the clinical drug trial will be a success or improve the volunteer’s symptoms. In some cases, the drug trialled may be no better or worse than their current treatment. Clinical trials test the safety and efficacy of new drugs and so involve potential risks, and it is crucial that volunteers fully understand what is involved in the clinical trial before agreeing to take part. Volunteers for clinical trials are always screened to assess their suitability for the trial and will be fully informed of the risks associated with the trial during this screening process.

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