Depression and Erectile Dysfunction

£690 plus reasonable travel expenses or transport provided

About This clinical research study

Here at MAC Clinical Research we are currently running a trial to test a new treatment for depression and erectile dysfunction (ED). You must have depression and ED to take part in this study and not currently taking any depression treatment.

Depression is a low mood disorder where a person will be persistently feeling sad and experience loss of interest. These feelings, thoughts and behaviours can lead to a variety of emotional and physical illnesses (including sexual problems).

Erectile dysfunction or erectile problems are terms used to describe when a man is unable to develop or sustain an erection, which can lead to difficulties in having sexual intercourse and low libido.

The study drug is a new compound which works by enhancing the effects of substances in the body such as serotonin and dopamine to help stimulate an erection. The study drug is being developed in the hope that it will treat depression and ED in men for whom current treatments either do not work or are poorly tolerated.

£690 plus reasonable travel expenses or transport provided


Greater Manchester

Therapy Area

Mental Health

Gender and Age

Males aged between 18 - 55

A full description of the study will be given before you decide to take part, both over the phone and during an appointment at the MAC clinic. This will include you receiving the full patient information sheet (PIS). Your GP will also be notified of your participation.

If you contact us, it does not mean you have to decide at that point whether to participate.
If you do decide to participate you are free to withdraw at any time.

The main aims of this study are:

  • To assess the effect of the study drug on the body
  • To assess the safety and tolerability of the study drug
  • To see how the body absorbs and removes the study drug


If you are eligible following medical screening, you will receive 2 doses of study medication and one dose of placebo. You will be required to attend 6 visits to the MAC Manchester clinic and on 4 occasions you will be asked to apply a Rigiscan device to your penis.  This is a piece of equipment which measures the strength of the erection you get whilst watching an “Adult” film in a private room.

Reimbursement: £690 plus reasonable travel expenses or transport provided

Key Inclusion Criteria

Key Exclusion Criteria

Other eligibility criteria will apply. Please contact MAC for more information.

Eligible patients will receive a health screen and study participation will be in collaboration with the patient’s treating physician.


Clinical research studies are performed as a way of bringing about progress in medicine and research. Clinical research studies make it possible to scientifically assess the properties of a drug, to demonstrate the effectiveness and safety of a treatment or a medical device, or to learn more about a disease and methods to diagnose and monitor it.

If the study is successful, it may be an important step towards developing a promising new treatment.

MAC Clinical Research is conducting a trial to evaluate a potential new treatment for depression and erectile dysfunction.

If you would like more information, please fill in the form below and we will be in touch…

Alternatively, please call our recruitment team on freephone 0800 633 5507.

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