Chronic Antibiotic Resistant Pouchitis
Enrolling Now

Clinics: Greater Manchester, Lancashire, Merseyside, South Staffordshire and West Yorkshire

Therapy Area: Antibiotic Resistant Pouchitis

Gender and Age: Males and females aged 18 – 75 (inclusive)

Reimbursement: Up to £1,135, which includes reasonable travel expenses.

About The Research...

Are you living with pouchitis after a surgeon has removed your colon and rectum because of complications due to ulcerative colitis? At some point you may have one or more flare-ups (inflammations) of your pouch. Pouch inflammation is called pouchitis. These flares can cause ongoing crampy lower abdominal pain, diarrhoea, fever, joint pain, and an urgent need to have bowel movements.

This trial will test the effect of AMT-101 (the investigational study drug) compared to placebo (inactive pill) on symptoms of pouchitis. There will be between 8 and 11 visits to one of our clinics over approximately 20-weeks. The study drug or placebo is to be taken orally once daily.

Reimbursement:  Up to £1,135, which includes reasonable travel expenses.

Criteria

Key Inclusion Criteria:

  • Male or female aged 18 – 75 years (inclusive)
  • Diagnosis of pouchitis with a history of ulcerative colitis, with pouch surgery performed at least one year ago
  • Pouch inflammation that is not resolved with antibiotics

 

Key Exclusion Criteria:

  • Diagnosis of Irritable Pouch Syndrome
  • Diagnosis of Crohn’s Disease or pouch Crohn’s Disease
  • Mechanical complications of the pouch

 

Other eligibility criteria will apply. Please contact MAC for more information.

Any other information

Eligible patients will receive a comprehensive health screen and study participation will be in collaboration with the participants’ treating physician.

Key Inclusion Criteria

  •  

Key Exclusion Criteria

  •  

MAC Clinical Research is currently conducting a new clinical research study for Pouchitis.

If you would like more information, please fill in the form below and we will be in touch…

Alternatively, please call our recruitment team on freephone 0800 633 5507.

  • Hidden
  • (You can enter any supporting information here)
  • Hidden
  • Hidden
  • Hidden
  • Hidden
  • Hidden
Data Privacy Statement

Know someone who may be interested in taking part? Share this page here:

Share on facebook
Facebook
Share on twitter
Twitter
Share on whatsapp
WhatsApp
Share on email
Email