Healthy Volunteers

Clinics: Greater Manchester Late Phase Unit

Therapy Area: Healthy Volunteers

Gender and Age: Males aged 18 – 65

Reimbursement: £2320 plus reasonable travel expenses

About The Research...

We are currently working to develop treatments which could be used to treat several nervous system conditions. However, we need healthy male volunteers to make this happen.

45 healthy male participants will take part in this study at our Greater Manchester clinic.

Participants will be required to attend 13 visits over approx. 10 months and the trial will assess and compare the safety and tolerability of three study medications (all marketed products): Dysport, Botulinum Toxin or Xeomin.

Interested volunteers will be required to undergo a full medical screening and those who are eligible will receive one single injection of either Dysport, Botulinum Toxin or Xeomin into the muscle on the outer side of the foot to induce a temporary weakness. Any weakness in this muscle caused by the study drugs will have no impact on walking. It is only upon review of your screening results and medical history that will we know if you are suitable to take part in the study.

The results of the study may help provide treatment options for people living with nervous system conditions e.g., involuntary spasms, cramps and tremors and aesthetic or beauty treatments e.g., reducing the appearance of facial lines.

A full description of the study will be given before you decide to take part, both over the phone and during an appointment at a MAC clinic. This will include you receiving the full patient information sheet (PIS). Your GP will also be notified of your participation.

Clinics: Greater Manchester Late Phase Unit

Reimbursement: £2320 plus reasonable travel expenses


Key Inclusion Criteria:

  • Male aged 18 to 65.
  • BMI 18 to 30 kg/m2.
  • Must be in good health as determined by medical and psychiatric history, medical examination, ECG and blood tests.


Key Exclusion Criteria:

  • Concerns about having blood taken.
  • Currently using any prescription or over the counter (OTC) medications.
  • Received Botulinum Toxin treatments in the last 6 months
  • Pending foot surgery
  • Diagnosis of any nerve related conditions e.g., diabetic foot pain or any neuromuscular conditions e.g., myasthenia gravis


Other eligibility criteria will apply. Please contact MAC for more information.

Any other information
If you are eligible, you will receive a comprehensive health screen. Your GP will be fully informed of your participation and provided with any information relevant to your healthcare.

Key Inclusion Criteria


Key Exclusion Criteria


MAC Clinical Research is currently conducting a new clinical research study for Male Healthy Volunteers.

If you would like more information, please fill in the form below and we will be in touch…

Alternatively, please call our recruitment team on freephone 0800 633 5507.

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