Erectile Dysfunction (ED)
Clinical Trial
MAC is testing a study medication which is being developed to treat Erectile Dysfunction (ED)
Improving quality of life
Key Information
Reimbursement
Receive up to £1496 plus reasonable travel costs
Gender and Age
Males aged 18 - 59
Clinics
Greater Manchester, Lancashire, Merseyside, South Staffordshire, South Yorkshire, Teesside and West Yorkshire
Health Check
Receive a free comprehensive health check
Register Your Interest
What Happens Next?
1. Sign Up
Register your interest on our website or over the phone
2. We'll Call You
Our study specialists will speak with you to discuss your health and check if the trial is suitable for you
3. Eligible?
If eligible, you will be booked in for a Chat where you'll receive a Patient Information Sheet (PIS)
4. Medical History
If you decide to take part, our medical team will obtain a copy of your medical history from your GP
5. Health Check
You will attend a free comprehensive health check with a MAC doctor and your eligibility will be confirmed
6. Enrollment
You will be enrolled onto the clinical trial and attend scheduled visits (Travel expenses or transport to clinic provided)
About this Erectile Dysfunction Clinical Trial
The study drug is a new compound which works by enhancing the effects of substances in the body such as serotonin and dopamine to help stimulate an erection. By participating in this clinical trial, you may be helping to contribute to the development of a new treatment for ED that may help improve the quality of life for many people.
– Age 18 – 59
– BMI 18 – 35 kg/m2
– Has erectile dysfunction but is otherwise healthy
Eligible patients will receive a health screen and study participation will be in collaboration with the patient’s treating physician.
– A history of psychiatric conditions or CNS problems such as stroke or epilepsy
– Unstable health conditions such as heart, lung, liver, digestive, or kidney disease or diabetes
(Further restrictions may apply depending on your medical history).
The study will run over two months, and you will need to visit the clinic seven times.
At four of the visits, you will take a dose of the medication, or a placebo (a pill with no active medication in it) and then be asked to fill in a sexual activity questionnaire. Neither you nor the doctor will know whether you are taking the medication or the placebo.
Some patients may be asked to provide either a sperm sample or use a Rigiscan* device as part of the study.
A full description of the study will be given before you decide to take part, both over the phone and during an appointment at the MAC clinic. This will include you receiving the full patient information sheet (PIS). Your GP will also be notified of your participation.
If you contact us, it does not mean you have to decide at that point whether to participate. If you do decide to participate you are free to withdraw at any time.
Receive up to £1496 plus reasonable travel costs.
Frequently Asked Questions
Erectile dysfunction is when a man is unable to develop or sustain an erection, which can lead to difficulties in having sexual intercourse. It is thought that up to 1 in 4 men have experienced ED at some point.
It is possible to buy medications such as Viagra, Cialis and Levitra from a pharmacy that can help with ED. However, these medications are effective in some men, but approximately 30% to 40% do not respond to this treatment.
Current ED treatments work by increasing blood flow to the periphery once an erection has begun. The latest research concentrates on the signalling pathway from the brain that initiates an erection as well as increasing blood flow.
Clinical trials are highly regulated medicine trials that help to bring about progress in health research. Clinical trials make it possible to scientifically assess the properties of an investigative medication, to demonstrate the effectiveness and safety of a treatment or a medical device, or to learn more about a disease and methods to diagnose and monitor it. If the trial is successful, it may be an important step towards developing a promising new treatment.
All clinical trials must be reviewed and authorised by various governing bodies and committees before they can go ahead to minimise any risks. The Medicines and Healthcare products Regulatory Agency (MHRA) ensures that medicines meet applicable standards of safety, quality and efficacy, meaning a trial must be thought to be safe before it is approved. The Health Research Authority (HRA) is responsible for research ethics committees across the UK. Independent research ethics committees work to protect the interests and rights of volunteers who take part in the trial, adding another layer of protection to the process.
If you a male, at least 18 years of age and have erectile dysfunction/impotence you may be eligible to take part. Other eligibility criteria will apply.
Before being accepted into a clinical trial, you must undergo a full health check to ensure you are physically and mentally fit to take part. The researchers conduct cognitive and physical tests during the health check, including height, weight, blood pressure, electrocardiogram and a review of your medical history. Dependent on the nature of the trial, validated health or condition-specific surveys may have to be completed – including, mental health assessment scales, health surveys and pain scores.
