Erectile Dysfunction (ED)
Clinical Trial

MAC is testing a study medication which is being developed to treat Erectile Dysfunction (ED)

Improving quality of life

Key Information


Receive up to £1496 plus reasonable travel costs

Gender and Age

Males aged 18 - 59


Greater Manchester, Lancashire, Merseyside, South Staffordshire, South Yorkshire, Teesside and West Yorkshire

Health Check

Receive a free comprehensive health check

Register Your Interest

Data Privacy Statement
“Around 4.3 million men in the UK experience erectile problems, but the current treatments available do not work adequately in around 40% of men, which highlights an unmet need for effective medicines to help treat ED. At MAC, we are testing a study drug which is thought to target the dopamine signalling pathway in the brain to help with erectile dysfunction. The development of this new potential treatment is only possible with the dedicated support of men with issues around ED volunteering to help assess the new treatments at MAC’s clinical research centres.”
Dr John Connell
Chief Scientific Officer

What Happens Next?

What happens next?

1. Sign Up

Register your interest on our website or over the phone

2. We'll Call You

Our study specialists will speak with you to discuss your health and check if the trial is suitable for you

3. Eligible?

If eligible, you will be booked in for a Chat where you'll receive a Patient Information Sheet (PIS)

4. Medical History

If you decide to take part, our medical team will obtain a copy of your medical history from your GP

5. Health Check

You will attend a free comprehensive health check with a MAC doctor and your eligibility will be confirmed

6. Enrollment

You will be enrolled onto the clinical trial and attend scheduled visits (Travel expenses or transport to clinic provided)

About this Erectile Dysfunction Clinical Trial

The study drug is a new compound which works by enhancing the effects of substances in the body such as serotonin and dopamine to help stimulate an erection. By participating in this clinical trial, you may be helping to contribute to the development of a new treatment for ED that may help improve the quality of life for many people.

Frequently Asked Questions

Erectile dysfunction is when a man is unable to develop or sustain an erection, which can lead to difficulties in having sexual intercourse. It is thought that up to 1 in 4 men have experienced ED at some point.

It is possible to buy medications such as Viagra, Cialis and Levitra from a pharmacy that can help with ED. However, these medications are effective in some men, but approximately 30% to 40% do not respond to this treatment.

Current ED treatments work by increasing blood flow to the periphery once an erection has begun.  The latest research concentrates on the signalling pathway from the brain that initiates an erection as well as increasing blood flow.

Clinical trials are highly regulated medicine trials that help to bring about progress in health research. Clinical trials make it possible to scientifically assess the properties of an investigative medication, to demonstrate the effectiveness and safety of a treatment or a medical device, or to learn more about a disease and methods to diagnose and monitor it. If the trial is successful, it may be an important step towards developing a promising new treatment.

All clinical trials must be reviewed and authorised by various governing bodies and committees before they can go ahead to minimise any risks. The Medicines and Healthcare products Regulatory Agency (MHRA) ensures that medicines meet applicable standards of safety, quality and efficacy, meaning a trial must be thought to be safe before it is approved. The Health Research Authority (HRA) is responsible for research ethics committees across the UK. Independent research ethics committees work to protect the interests and rights of volunteers who take part in the trial, adding another layer of protection to the process.

If you a male, at least 18 years of age and have erectile dysfunction/impotence you may be eligible to take part. Other eligibility criteria will apply.

Before being accepted into a clinical trial, you must undergo a full health check to ensure you are physically and mentally fit to take part. The researchers conduct cognitive and physical tests during the health check, including height, weight, blood pressure, electrocardiogram and a review of your medical history. Dependent on the nature of the trial, validated health or condition-specific surveys may have to be completed – including, mental health assessment scales, health surveys and pain scores.

Would you like to keep up to date with clinical research opportunities?