Knee Osteoarthritis Clinical Trial

Clinics: Greater Manchester EPU

Therapy Area: Osteoarthritis

Gender and Age: Males & Females aged 40 – 75

Reimbursement: Up to £3134 plus reasonable travel

MAC Osteoarthritis Clinical Trial

About The Research...

MAC Clinical Research is currently running a study to trial a potential new treatment for osteoarthritis of the knee. Previous research shows that the trial drug is designed to block the activity of a substance called CCL17 by attaching to it. CCL17 is a protein released by cells which has been shown to cause inflammation and joint pain and it is hoped that by blocking it, the trial drug may reduce inflammation and improve symptoms in people with OA pain. The main objective for this trial is to assess changes in pain in participants with OA of the knee following repeat subcutaneous dosing.

The trial will involve up to 23 visits to our clinic in Greater Manchester plus one telephone call over a 26 week period.

Reimbursement: Up to £3134 plus reasonable travel


* Key Inclusion Criteria:

  • Male or female aged 40 – 75
  • Features and symptoms of osteoarthritis knee which meet the specific study criteria
  • BMI between 19-34.9 kg/m²


* Key Exclusion Criteria:

  • Diagnosis of any other arthritis, pain condition or autoimmune disease (e.g. rheumatoid arthritis, other inflammatory arthritis, acute joint trauma, gout, pseudo gout, Paget’s disease, fibromyalgia, osteonecrosis)
  • Any surgery including open knee surgery or arthroscopic (“keyhole”) surgery within the past 3 months
  • History of any major cardiac or vascular event within the past 6 months


Other eligibility criteria will apply. Please contact MAC for more information.

Any other information

Eligible patients will receive a comprehensive health screen and study participation will be in collaboration with the participants’ treating physician.

Key Inclusion Criteria


Key Exclusion Criteria


MAC Clinical Research is conducting a trial to evaluate a potential new treatment for Osteoarthritis of the Knee.

If you would like more information, please fill in the form below and we will be in touch…

Alternatively, please call our recruitment team on freephone 0800 633 5507.

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